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DGI:ZNS-Infektionen/Nosokomiale Ventrikulitis und Meningitis/Quellen: Unterschied zwischen den Versionen

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28. <span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;mso-tab-count:1&quot;}" style="box-sizing: inherit;">          <span> </span></span>Tunkel AR, Hasbun R, Bhimraj A, Byers K, Kaplan SL, Michael Scheld W, van de Beek D, Bleck TP, Garton HJ, Zunt JR: 2017 Infectious Diseases Society of America's Clinical Practice Guidelines for Healthcare-Associated Ventriculitis and Meningitis. Clin Infect Dis 2017; 64: e34–e65
# <span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;box-sizing: inherit;&quot;}" style="box-sizing: inherit;">Ambulant erworbene bakterielle (eitrige) Meningoenzephalitis im Erwachsenenalter, AWMF-Registernummer: 030/089 [</span>https://www.awmf.org/leitlinien/detail/ll/030-089.html<span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;box-sizing: inherit;&quot;}" style="box-sizing: inherit;">]</span>
# Beer R et al. Nosocomial ventriculitis and meningitis in neurocritical care patients. <span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;mso-ansi-language:DE&quot;}" style="box-sizing: inherit;">J Neurol 2008; 255(11):1617-1624</span>
# Karvouniaris M et al. The Role of Intraventricular Antibiotics in the Treatment of Nosocomial Ventriculitis/Meningitis from Gram-Negative Pathogens: A Systematic Review and Meta-Analysis. World Neurosurg 2018; 120:e637-e650
# Mader MM et al. Intrathecal penetration of meropenem and vancomycin administered by continuous infusion in patients suffering from ventriculitis-a retrospective analysis. Acta Neurochir (Wien) 2018; 160(11):2099-2105
# Nau R et al. Pharmacokinetics and pharmacodynamics of antibiotics in central nervous system infections. Curr Opin Infect Dis 2018; 31(1):57-68
# Nau R et al. Intrathecal Antibacterial and Antifungal Therapies. Clin Microbiol Rev 2020; 33(3)
# Nau R et al. Penetration of drugs through the blood-cerebrospinal fluid/blood-brain barrier for treatment of central nervous system infections. Clin Microbiol Rev 2010; 23(4):858-883
# Nau R et al.  Pharmacokinetic optimisation of the treatment of bacterial central nervous system infections. Clin Pharmacokinet 1998; 35(3):223-246
# Reyes MM et al. : Comparing External Ventricular Drains-Related Ventriculitis Surveillance Definitions. Infect Control Hosp Epidemiol 2017; 38(5):574-579
# Tangden T et al. Neurosurgical gram-negative bacillary ventriculitis and meningitis: a retrospective study evaluating the efficacy of intraventricular gentamicin therapy in 31 consecutive cases. Clin Infect Dis 2011; 52(11):1310-1316
# Tunkel AR et al. 2017 Infectious Diseases Society of America's Clinical Practice Guidelines for Healthcare-Associated Ventriculitis and Meningitis. Clin Infect Dis 2017; 64: e34–e65  
# Kohlmann R et al. Effect of ampC derepression on cefepime MIC in Enterobacterales with chromosomally encoded inducible AmpC β-lactamase. Clin Microbiol Infect 2019, 25: 1158.e1-1158.e4


29. <span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;mso-tab-count:1&quot;}" style="box-sizing: inherit;">          <span> </span></span>Reyes MM, Munigala S, Church EL, Kulik TB, Keyrouz SG, Zipfel GJ, Warren DK: Comparing External Ventricular Drains-Related Ventriculitis Surveillance Definitions. Infect Control Hosp Epidemiol 2017; 38(5):574-579
30. <span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;mso-tab-count:1&quot;}" style="box-sizing: inherit;">          <span> </span></span>Beer R, Lackner P, Pfausler B, Schmutzhard E: Nosocomial ventriculitis and meningitis in neurocritical care patients. <span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;mso-ansi-language:DE&quot;}" style="box-sizing: inherit;">J Neurol 2008; 255(11):1617-1624</span>
<span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;mso-ansi-language:\nDE&quot;}" style="box-sizing: inherit;">31. <span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;mso-tab-count:1&quot;}" style="box-sizing: inherit;">          <span> </span></span>Ambulant erworbene bakterielle (eitrige) Meningoenzephalitis im Erwachsenenalter, AWMF-Registernummer: 030/089 [</span>https://www.awmf.org/leitlinien/detail/ll/030-089.html<span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;mso-ansi-language:DE&quot;}" style="box-sizing: inherit;">]</span>
32. <span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;mso-tab-count:1&quot;}" style="box-sizing: inherit;">          <span> </span></span>Nau R, Blei C, Eiffert H: Intrathecal Antibacterial and Antifungal Therapies. Clin Microbiol Rev 2020; 33(3)
33. <span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;mso-tab-count:1&quot;}" style="box-sizing: inherit;">          <span> </span></span>Karvouniaris M, Brotis AG, Tsiamalou P, Fountas KN: The Role of Intraventricular Antibiotics in the Treatment of Nosocomial Ventriculitis/Meningitis from Gram-Negative Pathogens: A Systematic Review and Meta-Analysis. World Neurosurg 2018; 120:e637-e650
34. <span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;mso-tab-count:1&quot;}" style="box-sizing: inherit;">          <span> </span></span>Nau R, Seele J, Djukic M, Eiffert H: Pharmacokinetics and pharmacodynamics of antibiotics in central nervous system infections. Curr Opin Infect Dis 2018; 31(1):57-68
35. <span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;mso-tab-count:1&quot;}" style="box-sizing: inherit;">          <span> </span></span>Nau R, Sorgel F, Eiffert H: Penetration of drugs through the blood-cerebrospinal fluid/blood-brain barrier for treatment of central nervous system infections. Clin Microbiol Rev 2010; 23(4):858-883
36. <span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;mso-tab-count:1&quot;}" style="box-sizing: inherit;">          <span> </span></span>Nau R, Sorgel F, Prange HW: Pharmacokinetic optimisation of the treatment of bacterial central nervous system infections. Clin Pharmacokinet 1998; 35(3):223-246
37. <span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;mso-tab-count:1&quot;}" style="box-sizing: inherit;">        <span> </span></span>Mader MM, Czorlich P, Konig C, Fuhrmann V, Kluge S, Westphal M, Grensemann J: Intrathecal penetration of meropenem and vancomycin administered by continuous infusion in patients suffering from ventriculitis-a retrospective analysis. Acta Neurochir (Wien) 2018; 160(11):2099-2105
38. <span class="ve-pasteProtect" data-ve-attributes="{&quot;style&quot;:&quot;mso-tab-count:1&quot;}" style="box-sizing: inherit;">        <span> </span></span>Tangden T, Enblad P, Ullberg M, Sjolin J: Neurosurgical gram-negative bacillary ventriculitis and meningitis: a retrospective study evaluating the efficacy of intraventricular gentamicin therapy in 31 consecutive cases. Clin Infect Dis 2011; 52(11):1310-1316
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Aktuelle Version vom 1. September 2026, 12:42 Uhr

  1. Ambulant erworbene bakterielle (eitrige) Meningoenzephalitis im Erwachsenenalter, AWMF-Registernummer: 030/089 [https://www.awmf.org/leitlinien/detail/ll/030-089.html]
  2. Beer R et al. Nosocomial ventriculitis and meningitis in neurocritical care patients. J Neurol 2008; 255(11):1617-1624
  3. Karvouniaris M et al. The Role of Intraventricular Antibiotics in the Treatment of Nosocomial Ventriculitis/Meningitis from Gram-Negative Pathogens: A Systematic Review and Meta-Analysis. World Neurosurg 2018; 120:e637-e650
  4. Mader MM et al. Intrathecal penetration of meropenem and vancomycin administered by continuous infusion in patients suffering from ventriculitis-a retrospective analysis. Acta Neurochir (Wien) 2018; 160(11):2099-2105
  5. Nau R et al. Pharmacokinetics and pharmacodynamics of antibiotics in central nervous system infections. Curr Opin Infect Dis 2018; 31(1):57-68
  6. Nau R et al. Intrathecal Antibacterial and Antifungal Therapies. Clin Microbiol Rev 2020; 33(3)
  7. Nau R et al. Penetration of drugs through the blood-cerebrospinal fluid/blood-brain barrier for treatment of central nervous system infections. Clin Microbiol Rev 2010; 23(4):858-883
  8. Nau R et al. Pharmacokinetic optimisation of the treatment of bacterial central nervous system infections. Clin Pharmacokinet 1998; 35(3):223-246
  9. Reyes MM et al. : Comparing External Ventricular Drains-Related Ventriculitis Surveillance Definitions. Infect Control Hosp Epidemiol 2017; 38(5):574-579
  10. Tangden T et al. Neurosurgical gram-negative bacillary ventriculitis and meningitis: a retrospective study evaluating the efficacy of intraventricular gentamicin therapy in 31 consecutive cases. Clin Infect Dis 2011; 52(11):1310-1316
  11. Tunkel AR et al. 2017 Infectious Diseases Society of America's Clinical Practice Guidelines for Healthcare-Associated Ventriculitis and Meningitis. Clin Infect Dis 2017; 64: e34–e65
  12. Kohlmann R et al. Effect of ampC derepression on cefepime MIC in Enterobacterales with chromosomally encoded inducible AmpC β-lactamase. Clin Microbiol Infect 2019, 25: 1158.e1-1158.e4


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